A quick assessment of the teams that jump out as being the top 3:
NecroVlade will have an interesting run to the playoffs now that Boozer has broken his hand, but his team is looking tight. This will be a tough matchup from week to week, although not weighted towards the guard stats.
Zombie Apocalypse has a great guard team that will dominate small ball stats from week to week, with some good scorers and rebounders as well. It will be interesting to see how far this team goes.
Umbrella Corp has put together a good mix of talented players, Tyreke Evans and DeMarcus Cousins on the same roster should be an exciting year. Amare, Jrue and Derrick can only get better. We'll see if the same will be said of DJ, Harden, Joakim, Millsap and Scola.